Contact Information:
Faizah Bhatti

 

Bhatti, Faizah (HSC)
Faculty

Department of:

College Of Medicine/Peds - Neonatology -Assistant Professor

Center of:

Education:

Residency: Penn State Milton S. Hershey Medical Center, Hershey, PA     2007

Fellowship: Georgetown University Medical Center, Washing D.C.     2010

The Aga Khan University Medical College, Karachi, Pakistan   MBBS   1998

Penn State College of Medicine, Hershey, PA   MS - Health Evaluation Sciences   2011

Professional Interest/Expertise/Specializations:
The focus of our lab is to study and characterize the collectin proteins Surfactant Proteins A and D in retinal biology. This is especially important in the context of retinal inflammation in the developing infant. These proteins appear to impact the developmental appearance of retinal blood vessels and thus influence retinal neovascularization seen in preterm infants. Our approach to this problem has been from both the basic science and clinical research side. From the molecular perspective, we are using mouse models of retinal inflammation and oxygen induced retinopathy to understand the pathways in retinal growth and blood vessel development during systemic and local retinal inflammation. From a translational aspect we are studying the genetic variation in surfactant proteins A and D in preterm babies with retinopathy of prematurity. Using this clinical-translational approach we hope to gain a better understanding of the various risk factors in the development of ROP, as currently the best therapies we currently offer, leave babies visually impaired for life.

Websites:

OU Children's Physicians - Department of Pediatrics

Research Projects:

Novel Inflammatory Mediators in Oxygen Induced Retinopathy

Risk Factors for Surgical Necrotizing Enterocolitis in VLBW Infants Admitted to a Tertiary Care Neonatal Unit

Selected Publications:

Transient Tachypnea of the Newborn iin Pediatrics, A Competency-Based Companion 2011    McMahon M, Stryjewski G, Bhatti, F Elsevier

17beta-estradiol Supplementation Reduces Tubulointerstitial Fibrosis by Increasing MMP Activity in the Diabetic Kidney 2007    Mankhey RW, Wells CC, Bhatti F Am J Physiol Regul Integr Comp Physiol

Diabetic Nephropathy is Associated with Decreased Circulating Estradiol Levels and Imbalance in the Expression of Renal Estrogen Receptors 2005    Wells CC, Riazi S, Mankhey RW, Bhatti F, Ecelbarger CA, Maric C Gend Med

Mechanisms of Antioxidant and Pro-oxidant Effects of Alpha-lipoic Acid in the Diabetic and Non-Diabetic Kidney 2005    Bhatti F, Mankhey RW, Asico L, Quinn MT, Welch WJ, Maric C Kidney Int