Mark L Lang

Contact Information:
Mark L Lang



 

Lang, Mark L. (HSC)
Associate Professor

Department of:

College Of Medicine/Microbiology & Immunology -Assistant Professor

Center of:

Education:

University of Dundee, Scotland   Ph.D.   1998

Professional Interest/Expertise/Specializations:
Dr. Lang and his team are researching the development and maintenance of antibody-mediated immunity also known as humoral immunity. The major focus is on mechanisms by which a specialized subset of T cells known as natural Killer-like T cells (NKT) are activated and in turn boost long-term humoral immunity. The laboratory has two specific goals: (i) understand the mechanisms by which NKT cells regulate long-term humoral immunity, (ii) apply the knowledge to develop novel vaccine strategies against pathogenic bacteria and viruses.

Websites:

Microbiology Website, Dr. Lang

Research Projects:

Selected Publications:

CD40L-null NKT cells provide B cell help for specific antibody responses
2011    H.B. Shah, S.K. Joshi, and M.L. Lang
Vaccine
http://www.sciencedirect.com/science/article/pii/S0264410X11014678
Regulation of anthrax toxin-specific antibody titers by Natural Killer T cell-derived IL-4 and IFN┬┐
2011    T.S. Devera, S.K. Joshi, L.M. Aye, G.A. Lang, J.D. Ballard and M.L. Lang
PLOS One
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0023817
Reduction of CD1d expression in vivo minimally affects NKT-enhanced Ab production but boosts B cell memory
2011    G.A. Lang, A.M. Johnson, T.S. Devera, S.K. Joshi, and M.L. Lang
International Immunology
http://intimm.oxfordjournals.org/content/23/4/251.long
Keywords, Tags:
NKT, anthrax, bioterrorism,