Mohammad Madhoun

Contact Information:
Mohammad Madhoun


Madhoun, Mohammad (HSC)

Department of:

College Of Medicine/Medicine - Gastroenterology -Associate Professor of Medicine

Center of:


Jordan University of Sciences and Technology   MD   2003
King Hussein Cancer, Jordan   Residency   2005
Department of Internal Medicine, University of Oklahoma HSC   Residency   2008
University of Oklahoma HSC   Gastroenterology Fellowship   2011
University of Oklahoma HSC   MSCTS   2011

Professional Interest/Expertise/Specializations:
Dr. Madhoun is very interested in clinical and translational research. His research interest include colorectal cancer screening, quality colonoscopy, and cancer stem cell markers in hepatocellular carcinoma and other gastrointestinal malignancies.


Department of Internal Medicine-Section of Digestive Diseases and Nutrition
Department of Internal Medicine-Faculty Listing
Veterans Affairs Medical Center-Physician Listing

Research Projects:

1. VA Office of Research, Cooperative Studies Program: #577 Randomized Trial of Colonoscopy versus Fecal Immunochemical Testing for Colorectal Cancer Screening, Local Site PI- Oklahoma City VA Medical Center 3/2012-2024
2. ASGE Quality in Endoscopic Research Award: Use of Diphenhydramine as an Adjunctive Sedative for Colonoscopy in Patients Chronically on Opioids, CO-PI 5/2014-6/2015
3. South Central VA Health Care Network (SCVAHCN) Research Grants: Efficacy and Tolerability of Various Bowel Preparations in Patients with Diabetes: A Randomized Controlled Trial, PI 10/2014-10/2016

Selected Publications:

Erratum to: The Impact of Chronic Opioid Use on Colonoscopy Outcomes
2015    Nusrat S, Mahmood S, Bitar H, Tierney WM, Bielefeldt K, Madhoun MF
Dig Dis Sci. 2015 Sep;60(9):2850. doi: 10.1007/s10620-015-3702-0 PMID: 25986520*~hmac=2b99417981703db622e6eb9b8de7cf7450
The impact of chronic opioid use on colonoscopy outcomes.
2015    Nusrat S, Mahmood S, Bitar H, Tierney WM, Bielefeldt K, Madhoun MF
Dig Dis Sci. 2015 Apr;60(4):1016-23. doi: 10.1007/s10620-015-3639-3. Epub 2015 Mar 31 PMID: 25822037*~hmac=fc8db9376650a8d09590a39b4d81a345d3
Effect of hyoscine N-butylbromide on adenoma detection rate: Meta-analysis of randomized clinical trials
2015    Madhoun MF, Ali T, Tierney WM, Maple JT
Dig Endosc. 2015 Mar;27(3):354-60. Epub 2014 Oct 16. PMID: 25115416
Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism.
2015    Sureban SM, Madhoun MF, May R, Qu D, Ali N, Fazili J, Weygant N, Chandrakesan P, Ding K, Lightfoot SA, Houchen CW
Oncotarget. 2015 Nov 10;6(35):37200-15. doi: 10.18632/oncotarget.5808 PMID: 26468984[]=5808&pubmed-linkout=1
DCLK1 is detectable in plasma of patients with Barrett's esophagus and esophageal adenocarcinoma
2015    Whorton J, Sureban SM, May R, Qu D, Lightfoot SA, Madhoun M, Johnson M, Tierney WM, Maple JT, Vega KJ, Houchen CW
Dig Dis Sci. 2015 Feb;60(2):509-13. Epub 2014 Oct 5. PMID: 25283374
Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis.
2015    Qu D, Weygant N, May R, Chandrakesan P, Madhoun M, Ali N, Sureban SM, An G, Schlosser MJ, Houchen CW
PLoS One. 2015 Aug 18;10(8):e0134212. doi: 10.1371/journal.pone.0134212. eCollection 2015 PMID: 26285154
Stress as a risk factor for inflammatory bowel disease: more evidence from our OEF/OIF veterans?
2014    Ali T, Prammanasudh CS, Samuels JM, Madhoun MF
Am J Gastroenterol. 2014 Apr;109(4):604-5. PMID: 24698873
Cirrhosis and its complications: evidence based treatment
2014    Nusrat S, Khan MS, Fazili J, Madhoun MF
World J Gastroenterol. 2014 May 14;20(18):5442-60. PMID: 24833875
Patient prompting of their physician resulted in increased colon cancer screening referrals
2014    Le V, Syed S, Vega KJ, Sharma T, Madhoun MF, Srinivasan N, Houchen CW
World J Gastrointest Oncol. 2014 Jul 15;6(7):257-62. PMID: 25024817
Endoscopic papillary large balloon dilation reduces the need for mechanical lithotripsy in patients with large bile duct stones: a systematic review and meta-analysis
2014    Madhoun MF, Wani S, Hong S, Tierney WM, Maple JT
Diagn Ther Endosc. 2014;2014:309618. Epub 2014 Mar 6. PMID: 24729674
The diagnostic accuracy of 22-gauge and 25-gauge needles in endoscopic ultrasound-guided fine needle aspiration of solid pancreatic lesions: a meta-analysis.
2013    Madhoun MF, Wani SB, Rastogi A, Early D, Gaddam S, Tierney WM, Maple JT.
Endoscopy;45(2):86-92. PMID: 23307148
The Impact on Endoscopic Resource Utilization After a Targeted Intervention for Cost-Minimization of EGD and Colonoscopy
   Kaitha SR, Salem G, Zhao YD, Madhoun MF, Chen A, Tierney WM
Am J Gastroenterol. 2016 Aug 30. doi: 10.1038/ajg.2016.340. [Epub ahead of print] PMID: 27575709