Michelle C. Callegan

Contact Information:
Michelle C. Callegan


Callegan, Michelle C. (HSC)
Professor Department of Ophthalmology

Department of:

College Of Medicine/Ophthalmology -Professor

Center of:

OK Center for Neurosciences -Associate Director of Research


Louisiana State University, Baton Rouge LA   B.S., Microbiology   1988
LSU Medical Center, New Orleans LA   M.S., Microbiology, Immunology and Parasitology   1991
LSU Medical Center, New Orleans LA   Ph.D., Microbiology, Immunology and Parasitology   1995
University of Oklahoma Health Sciences Center, Oklahoma City OK   Post-Doctoral Fellow and Research Scientist   1999

Professional Interest/Expertise/Specializations:


OU Vision Website

Research Projects:

PI - "New Models of Endogenous Bacterial Endophthalmitis"
PI- "Mechanisms of Inflammation and Vision Loss in Bacillus Endophthalmitis"
Director, Live Animal Imaging and Functional Analysis Module -"Core Grant for Vision Research"
Director, Animal Module - "Mentoring Vision Research in Oklahoma"

Selected Publications:

Hypermucoviscosity and TLR4 Interactions in Klebsiella pneumoniae Ocular Virulence.
2013    Hunt JJ, Astley R, Wang J-T, Callegan MC.
Submitted to Infect Immun, Dec 2012.
The impact of short term topical gatifloxacin and moxifloxacin on bacterial injection after hypodermic needle passage through human conjunctiva.
2013    Pettey JH, Mifflin MD, Kamae K, McEntire MW, Pettey DH, Callegan MC, Brown H, Olson RJ.
J Ocular Pharmacol Ther, accepted Dec 2012.
Endogenous endophthalmitis is associated with vascular permeability in diabetes.
2012    Coburn PC, Wiskur BJ, Callegan MC.
Invest Ophthalmol Vis Sci. 2012 Nov 1;53(12):7426-31. doi: 10.1167/iovs.12-10661. PMID: 23036996 PMCID:PMC3487485
Ocular inflammation and infection.
2012    Callegan MC, Gregory-Ksander M, Willcox M, Lightman S.
Int J Inflammation. 2012:1-2, 2012. doi:10.1155/2012/403520
Role of Toll-like receptor (TLR) 2 in experimental Bacillus cereus endophthalmitis.
2012    Novosad B, Astley R, Callegan MC.
PLoS ONE 6(12): e28619. doi:10.1371/journal.pone.0028619.
Role of capsular antigen in experimental Klebsiella pneumoniae endophthalmitis.
2011    Hunt JJ, Wang J-T, Callegan MC.
Invest Ophthalmol Vis Sci, Invest Ophthalmol Vis Sci. 2011 Aug 29;52(9):6860-6. Print 2011 Aug.
Severe Bacterial Endophthalmitis: Towards Improving Clinical Outcomes.
2010    Novosad B, Callegan MC.
Exp Rev Ophthalmol 5(5):689-698, 2010
Checks and balances: The ocular response to infection.
2010    Callegan MC
Virulence. 2010 Oct 27;1(4):222.
Bacterial endophthalmitis: Therapeutic challenges and host-pathogen interactions.
2007    Callegan MC, Gilmore MS, Gregory M, Ramadan R, Wiskur BJ, Moyer AL, Hunt JJ, Novosad BD.
Prog Retinal Eye Res Mar;26(2):189-203, 2007.
Role of bacterial and host factors in infectious endophthalmitis.
2007    Gregory M, Gilmore MS, Callegan MC.
Chem Immunol Allergy 92:266-75, 2007.
Bacterial endophthalmitis: Epidemiology, therapeutics, and bacterial/host interactions.
2002    Callegan MC, Englebert M, Parke DW, Jett BD, Gilmore MS.
Clin Microbiol Rev 15:111-124, 2002.
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