David M Sherry

Contact Information:
David M Sherry


Sherry, David M. (HSC)
Associate Professor

Department of:

College Of Medicine/Cell Biology -Associate Professor

Center of:

OK Center for Neurosciences -Member


University of Florida   PhD  

Professional Interest/Expertise/Specializations:
My lab has two principal research interests: 1) The architecture and development of neuronal circuitry, and 2) Polarization and migration of cells. The first project focuses on the maturation of specific cells and their circuits, using the retina as a model system. Specifically our studies concentrate on the development of synapses by retinal photoreceptors and the cells that participate in circuits specifically dedicated to processing information from rod photoreceptors (which mediate black and white, night vision) and cones (which mediate color, daylight vision). The second project is directed at understanding the mechanisms that are involved in the transition of differentiated cells to a polarized, migratory phenotype and the signals that regulate migratory behavior and guidance. Techniques utilized in the lab focus primarily on imaging approaches at the light, confocal and electron micrographic levels.


Research Projects:

Selected Publications:

Progression of Neuronal and Synaptic Remodeling in the rd10 Mouse Model of Retinitis Pigmentosa
   Phillips MJ, Otteson DC, Sherry DM
J Comp Neurol
Distribution of plasma membrane-associated syntaxins 1 through 4 indicates distinct trafficking functions in the synaptic layers of the mouse retina.
   Sherry DM, Mitchell R, Standifer KM, du Plessis B.
BMC Neurosci
Expression of vesicular glutamate transporter 1 in the mouse retina reveals temporal ordering in development of rod vs. cone and ON vs. OFF circuits.
   Sherry DM, Wang MM, Bates J, Frishman LJ.
J Comp Neurol
SV2 acts via presynaptic calcium to regulate neurotransmitter release
   Wan QF, Zhou ZY, Thakur P, Vila A, Sherry DM, Janz R, Heidelberger R.